Parkinson’s is a neurodegenerative disease of the central nervous system, caused by a deficiency of the neurotransmitter dopamine, vital to coordinate movements and balance of the human body. This deficiency
The British physician James Parkinson described the disease and documented for the first time in 1817 (Essay on the Shaking Palsy). Associated biochemical changes were described in the 60’s.
In Parkinson’s disease the progressive destruction of a specific region of the brain (the substantia nigra) leads to the appearance of symptoms. In the brain there is a group of nerve cells that produce dopamine. These neurons are grouped in a structure called black-substance by having a dark-colored bodies, which is situated in the basal ganglia (in the area between the brain and spinal cord). The neurons of the substantia nigra of patients with Parkinson’s disease die prematurely without being replaced by new ones.
When 50 or 60% of these cells disappear from this area become evident symptoms.
The cause of this disease is unknown. Multiple pathogenic hypotheses have emerged. Among the more informed are those involving a toxic factor, as yet unknown, and genetic factors. Whatever the ultimate cause, various known processes are likely involved in the production of neuronal damage. Including the formation of free radicals.
These compounds are unstable due to lack of an electron. In an attempt to replace missing electron, free radicals react with the surrounding molecules (especially metals such as iron) in a process called oxidation. It is considered that this process causes damage to the tissues that connect the neurons.
Normally, antioxidants (chemicals that protect cells from this damage) keep under control the damage caused by free radicals.
Other scientists have suggested that Parkinson’s disease can occur when an external or internal toxin selectively destroys dopaminergic neurons. An environmental risk factor such as exposure to pesticides or a toxin in the food supply, is an example of the kind of external trigger that could hypothetically cause Parkinson’s disease. The theory has among its supporters that some toxins, such as 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine (MPTP) induces symptoms similar to Parkinson’s disease and injuries neurons of the substantia nigra in human beings and animals. However, to date, no research has provided definitive proof that a toxin is the cause of the disease test.
Parkinson's Disease Remedies and Symptoms
Fatigue For people who suffer from Parkinson’s disease, fatigue can seem as much a state of mind and body. We know all about this common symptom, but we know that fatigue can respond to both physical and mental causes.
Sometimes, people who suffer from any kind of illness feel fatigue. This occurs when a muscle or group of muscles was too demanding for an activity or exercise. Often the stress of daily life, when done too much in too little time, causes fatigue. In Parkinson’s disease the feeling of fatigue is difficult to describe and even harder to measure. Many symptoms of Parkinson’s disease can cause a feeling of fatigue and might be difficult to complete an activity. Fatigue can mean slow movement, muscle rigidity, depression or even changes in the ability to move or sleep. Can be experienced throughout the day or just when you are ending the effect of drugs.
Fatigue caused by akinesia The akinesia, or difficulty initiating movement, often seems to fatigue. A person with this symptom should move slowly and will find it difficult to complete a task in a given time. Daily tasks such as dressing, may take long. People with Parkinson’s disease may, during the day, keep track of time in a time when his akinesia improvement and the medications are working. Daily tasks that require energy consumption can be made at the time when it is easier to move.
Muscle fatigue The symptoms of Parkinson’s disease, such as muscle stiffness, cramps, tremor (shaking) and difficulty initiating movement cause stress on the muscles of the affected people. To move with these symptoms, your muscles have to work hard and often against each other. With trembling, shaking constants can fatigue the muscles quickly. Parkinson medications can be used to treat these symptoms but should be carefully controlled to avoid a very common side effect called dyskinesia (involuntary movements agitated), because this side effect also causes fatigue. The muscles do not move enough longer in good condition and the size is reduced (atrophy). The loss of muscle strength decreases stamina and endurance and for many people, this decline seems to fatigue. The only treatment is a regular exercise program. People who included exercise as part of your daily routine with less fatigue.
Fluctuations in mobility Many people with Parkinson’s Disease in mobility fluctuates throughout the day. Generally these fluctuations coincide with dosage times, with an increase in symptoms at the end of a dose. It is also common to feel the greatest relief of symptoms in the morning, when people are well rested. Often people try to leave everything done in the morning, when it feels right, but on activity can lead to fatigue.
Exercise is important to counteract the effects of Parkinson’s disease. Below you will find some basic recommendations to maintain mobility.
Exercises to preserve mobility
IDEAL TO MAINTAIN MOBILITY AND IMPROVE SYMPTOMS.
The person with Parkinson must remain active to prevent progressive deterioration of motor product progress of their disease. For this reason, here you’ll find a series of exercises that are part of a program so you can maintain your physical and motor condition longer and improve their quality of life.
FOR A FLEXIBLE BODY
1 Sitting in a chair with your body straight, knees bent at an angle of 90 ° and the soles of the feet flat on the floor.
2 Take a cane or similar (a broomstick, for example) and support at both ends of the legs.
3 Inhale deeply and on the exhale, lift the cane above his head driving him near the trunk and following it sight ton.
4 Lower the cane to the ground (or as low as possible), a great arc forward.
5 Back slowly to the starting position. Repeat the exercise five times.
Other mobility exercises for hands and fingers
1 Open and close your hands and spread fingers closing completely.
2 Open and close each finger alternately.
3 Rotate the wrist to the right and then left.
4 Flex the wrist up and down keeping open hand.
5 Do the exercises with both hands and repeat several times during the day.